Scott Biller is the Head of Global Discovery Chemistry at the Novartis Institutes for BioMedical Research (NIBR). In this capacity, he is responsible for the combinatorial, medicinal and computational chemistry efforts across the NIBR sites in Basel, Swizerland, Cambridge, USA, Vienna, Austria and Horsham, UK.
Scott has more than 20 years of successful pharmaceutical discovery experience. Prior to joining NIBR, he held the position of Vice President, Pharmaceutical Candidate Optimization at the Bristol-Myers Squibb (BMS) Pharmaceutical Research Institute. Scott's work focused on the identification of superior drug candidates through the optimization of the physicochemical, ADME and safety attributes of molecules, in parallel with efficacy, in order to increase success rates from drug candidate nomination to launch. Prior to this position, he was the Head of Discovery Chemistry for the BMS Pharmaceutical Research Institute's Lawrenceville site. He was responsible for overseeing chemistry forĀ the following areas: oncology, immunology, inflammation, pulmonary diseases and cardiovascular diseases.
Among his other key leadership positions, Scott was the Executive Director of Metabolic Diseases Chemistry, with responsibility for medicinal chemistry programs in hypercholesterolemia and atherosclerosis, diabetes, obesity, osteoporosis and the endocrine dysfunction of the aging population. Under his leadership, this group delivered multiple clinical candidates, including a novel PPAR dual agonist for treatment of diabetes that is currently completing Phase III clinical trials.
Scott Biller has over 80 scientific papers and issued patents. He completed his BS degree at the Massachusetts Institute of Technology in 1976 where he did his undergraduate research with Nobel laureate K. Barry Sharpless. In 1982, he completed his PhD in Organic Chemistry at the California Institute of Technology under the tutelage of David Evans. Scott was awarded an NIH Postdoctoral Fellowship (1982-1983) in natural product synthesis at Columbia University with Gilbert Stork.
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